Pyridine, 3,5-difluoro-4-iodo- - Names and Identifiers
Pyridine, 3,5-difluoro-4-iodo- - Physico-chemical Properties
Molecular Formula | C5H2F2IN
|
Molar Mass | 240.98 |
Density | 2.129±0.06 g/cm3(Predicted) |
Boling Point | 184.2±35.0 °C(Predicted) |
pKa | -1.00±0.28(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Sensitive | Irritant |
MDL | MFCD13185558 |
Pyridine, 3,5-difluoro-4-iodo- - Risk and Safety
Pyridine, 3,5-difluoro-4-iodo- - Introduction
3,5-Difluoro-4-iodopyridine is an organic compound with the chemical formula C5H2F2IN and its properties are as follows:
1. Appearance: 3,5-difluoro-4-iodopyridine is a white to light yellow solid.
2. Solubility: It can be dissolved in organic solvents such as dimethyl sulfoxide (DMSO), acetonitrile and dichloromethane, but is insoluble in water.
3. Melting point: The melting point of 3,5-difluoro-4-iodopyridine is about 150-152°C.
4. Stability: It is relatively stable at room temperature, but may decompose in the presence of high temperature, sunlight and strong oxidants.
3,5-difluoro-4-iodopyridine has a wide range of applications in organic synthesis and is commonly used in the pharmaceutical field, especially as an intermediate in pharmaceuticals. It can also be used as an important raw material and catalyst in organic synthesis.
Method for preparing 3,5-difluoro-4-iodopyridine:
The reaction is usually carried out using iodoacetic acid and iron difluoride as starting materials. First, iron difluoride and sulfuric acid are reacted to obtain iron trifluoride; then, iron trifluoride and iodoacetic acid are reacted to produce 3,5-difluoro-4-iodopyridine.
About safety information:
1. 3,5-difluoro-4-iodopyridine is an organic compound and should follow general laboratory safety procedures.
2. During operation, attention should be paid to avoid contact with skin and eyes, and avoid inhaling its vapor or dust.
3. Store it in a sealed manner, away from fire and oxidizing agents, and store it in a dry place.
4. Dispose of waste in accordance with local regulations to avoid environmental pollution.
Last Update:2024-04-09 21:01:54